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. 1981 Jan 15;194(1):327–330. doi: 10.1042/bj1940327

Age-dependent decay of cytochrome b5 and cytochrome b5 reductase in human erythrocytes.

T Matsuki, M Tamura, M Takeshita, Y Yoneyama
PMCID: PMC1162747  PMID: 7305986

Abstract

Age-dependent decrease in cytochrome b5 was observed in erythrocytes from both a normal person and a patient with hereditary methaemoglobinaemia without neurological symptoms. With aging, concentrations of cytochrome b5 in erythrocytes from the patient were almost the same as those in the control. Age-dependent decrease in cytochrome b5 reductase activity in the control erythrocytes was also shown; however, the reductase activity was very low in erythrocytes from the patient over the whole age range. Our studies show that methaemoglobin content of erythrocytes seems to be dependent on the content of cytochrome b5 in the cells, both in the control subject and in the patient.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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