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. 1981 Jul 15;198(1):231–234. doi: 10.1042/bj1980231

Mitochondrial-membrane polar-head-group composition is influenced by diet fat.

S M Innis, M T Clandinin
PMCID: PMC1163233  PMID: 7325999

Abstract

Male Sprague-Dawley rats were fed diets containing 20% (w/w) soya-bean oil, high-erucic acid rapeseed oil or low-erucic acid rapeseed oil for 0, 12 or 23 days. The type of fat present in the diet had no effect on the total phospholipid content of heart mitochondria (micrograms/mg of protein) but did influence the phospholipid class distribution. Rats fed high-erucic acid rapeseed oil for 12 or 23 days had significantly higher mitochondrial phosphatidylcholine content than rats fed soya-bean oil. Low-erucic acid rapeseed oil resulted in elevation of cardiac mitochondrial cardiolipin content after dietary treatment for 12 days. The results demonstrate in vivo that diet is a significant determinant of the phospholipid class content of subcellular membranes.

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Selected References

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