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. 1981 Aug 15;198(2):353–356. doi: 10.1042/bj1980353

Mechanism of 3-phenylpyruvate-induced insulin release from isolated pancreatic islets.

U Panten, J Langer
PMCID: PMC1163255  PMID: 7034729

Abstract

3-Phenylpyruvate evoked a monophasic insulin release from perifused mouse islets. L-Phenylalanine was not an insulin secretagogue and was oxidized by islets at a very low rate, suggesting that 3-phenylpyruvate does not trigger insulin release by enhancing production of reducing equivalents. Moreover, allosteric activation of glutamate dehydrogenase does not play a role in 3-phenylpyruvate-induced insulin secretion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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