Skip to main content
PMC home page
Biochemical Journal logoLink to Biochemical Journal
. 1981 Aug 15;198(2):425–428. doi: 10.1042/bj1980425

Lipogenesis in vivo in maternal and foetal tissues during late gestation in the rat.

M Lorenzo, T Caldés, M Benito, J M Medina
PMCID: PMC1163268  PMID: 7326014

Abstract

The rate of 3H2O incorporation into lipid in vivo progressively decreased in liver but increased in parametrial adipose tissue during the last 3 days of gestation. These changes seem to be related to those occurring in plasma insulin and progesterone concentrations during the same period. Foetal liver showed a high rate of lipogenesis, which sharply decreased before parturition. foetal lung lipogenesis increased during days 20 and 21 of gestation.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEATON G. H., BEARE J., RYU M. H., McHENRY E. W. Protein metabolism in the pregnant rat. J Nutr. 1954 Oct 11;54(2):291–304. doi: 10.1093/jn/54.2.291. [DOI] [PubMed] [Google Scholar]
  2. Costrini N. V., Kalkhoff R. K. Relative effects of pregnancy, estradiol, and progesterone on plasma insulin and pancreatic islet insulin secretion. J Clin Invest. 1971 May;50(5):992–999. doi: 10.1172/JCI106593. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Eggstein M., Kreutz F. H. Eine neue Bestimmung der Neutralfette im Blutserum und Gewebe. I. Prinzip, Durchführung und Besprechung der Methode. Klin Wochenschr. 1966 Mar 1;44(5):262–267. doi: 10.1007/BF01747716. [DOI] [PubMed] [Google Scholar]
  4. Flint D. J., Sinnett-Smith P. A., Clegg R. A., Vernon R. G. Role of insulin receptors in the changing metabolism of adipose tissue during pregnancy and lactation in the rat. Biochem J. 1979 Aug 15;182(2):421–427. doi: 10.1042/bj1820421. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. GARLAND P. B., RANDLE P. J. A rapid enzymatic assay for glycerol. Nature. 1962 Dec 8;196:987–988. doi: 10.1038/196987a0. [DOI] [PubMed] [Google Scholar]
  6. HALES C. N., RANDLE P. J. Immunoassay of insulin with insulin-antibody precipitate. Biochem J. 1963 Jul;88:137–146. doi: 10.1042/bj0880137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hammond G. L., Viinikka L., Vihko R. Automation of radioimmunoassays for some sex steroids with use of both iodinated and tritiated ligands. Clin Chem. 1977 Jul;23(7):1250–1257. [PubMed] [Google Scholar]
  8. Hamosh M., Clary T. R., Chernick S. S., Scow R. O. Lipoprotein lipase activity of adipose and mammary tissue and plasma triglyceride in pregnant and lactating rats. Biochim Biophys Acta. 1970 Sep 8;210(3):473–482. doi: 10.1016/0005-2760(70)90044-5. [DOI] [PubMed] [Google Scholar]
  9. ITAYA K., UI M. COLORIMETRIC DETERMINATION OF FREE FATTY ACIDS IN BIOLOGICAL FLUIDS. J Lipid Res. 1965 Jan;6:16–20. [PubMed] [Google Scholar]
  10. Jones C. T. Lipid metabolism and mobilization in the guinea pig during pregnancy. Biochem J. 1976 May 15;156(2):357–365. doi: 10.1042/bj1560357. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. KOREN Z., SHAFRIR E. PLACENTAL TRANSFER OF FREE FATTY ACIDS IN THE PREGNANT RAT. Proc Soc Exp Biol Med. 1964 Jun;116:411–414. doi: 10.3181/00379727-116-29263. [DOI] [PubMed] [Google Scholar]
  12. KREBS H. A., BENNETT D. A., DE GASQUET P., GASQUET P., GASCOYNE T., YOSHIDA T. Renal gluconeogenesis. The effect of diet on the gluconeogenic capacity of rat-kidney-cortex slices. Biochem J. 1963 Jan;86:22–27. doi: 10.1042/bj0860022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Knopp R. H., Saudek C. D., Arky R. A., O'Sullivan J. B. 2 phases of adipose tissue metabolism in pregnancy: maternal adaptations for fetal growth. Endocrinology. 1973 Apr;92(4):984–988. doi: 10.1210/endo-92-4-984. [DOI] [PubMed] [Google Scholar]
  14. Krebs H. A., Dierks C., Gascoyne T. Carbohydrate synthesis from lactate in pigeon-liver homogenate. Biochem J. 1964 Oct;93(1):112–121. doi: 10.1042/bj0930112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Maniscalco W. M., Wilson C. M., Gross I., Gobran L., Rooney S. A., Warshaw J. B. Development of glycogen and phospholipid metabolism in fetal and newborn rat lung. Biochim Biophys Acta. 1978 Sep 28;530(3):333–346. doi: 10.1016/0005-2760(78)90153-4. [DOI] [PubMed] [Google Scholar]
  16. Martin C. E., Cake M. H., Hartmann P. E., Cook I. F. Relationship between foetal corticosteroids, maternal progesterone and parturition in the rat. Acta Endocrinol (Copenh) 1977 Jan;84(1):167–176. doi: 10.1530/acta.0.0840167. [DOI] [PubMed] [Google Scholar]
  17. SCOW R. O., CHERNICK S. S., BRINLEY M. S. HYPERLIPEMIA AND KETOSIS IN THE PREGNANT RAT. Am J Physiol. 1964 Apr;206:796–804. doi: 10.1152/ajplegacy.1964.206.4.796. [DOI] [PubMed] [Google Scholar]
  18. Stansbie D., Brownsey R. W., Crettaz M., Denton R. M. Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. Biochem J. 1976 Nov 15;160(2):413–416. doi: 10.1042/bj1600413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Sutter-Dub M. T., Leclercq R., Felix J. M., Jacquot R., Sutter B. C. Serum progesterone and immuno-reactive insulin levels in the pregnant rat. Horm Metab Res. 1973 Jan;5(1):18–21. doi: 10.1055/s-0028-1093994. [DOI] [PubMed] [Google Scholar]
  20. Weinhold P. A., Quade M. M., Brozowski T. B., Feldman D. A. Increased synthesis of phosphatidylcholine by rat lung following premature birth. Biochim Biophys Acta. 1980 Jan 18;617(1):76–84. doi: 10.1016/0005-2760(80)90225-8. [DOI] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES