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. 1981 Nov 15;200(2):429–433. doi: 10.1042/bj2000429

Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats.

P Ferré, P Satabin, L El Manoubi, S Callikan, J Girard
PMCID: PMC1163553  PMID: 7340842

Abstract

In hepatocytes from 1-day-old rats, active gluconeogenesis occurs in parallel with active ketogenesis, although the carbon atoms of non-esterified fatty acids do not participate in glucose synthesis. Once a significant ketogenesis is established, a further increase does not enhance gluconeogenesis. Indeed, octanoate is more ketogenic than oleate, but stimulates gluconeogenesis to a similar extent.

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Selected References

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