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. 1982 Mar 1;201(3):665–668. doi: 10.1042/bj2010665

The stereochemical course of phosphoryl transfer catalysed by glucose 6-phosphatase.

G Lowe, B V Potter
PMCID: PMC1163697  PMID: 6284126

Abstract

Rat liver microsomal glucose 6-phosphatase catalyses phosphoryl transfer between D-glucose 6-[(R)-16O,17O,18O]phosphate and D-glucose with retention of configuration at the phosphorus atom. Since individual phosphoryl-transfer steps appear in general to occur with inversion of configuration, this observation is most simply interpreted in terms of a double-displacement mechanism with a phosphoryl-enzyme intermediate. Such an intermediate has been proposed previously from kinetic and 32P-labelling experiments.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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