Table 1. Subjects' characteristics.
| All subjectsn=446 | MI(+) subjectsn=149 | MI(-) subjectsn=297 | p-value | ||||
|---|---|---|---|---|---|---|---|
| Male, n (%) | 257 (57.6) | 98 (66) | 159 (54) | 0.015 | |||
| Median age, years (Q1;Q3) | 76.4 (71.9;80.9) | 82.0 (78.0;86.0) | 73.6 (70.6;77.8) | p<10–4 | |||
| Cardiovascular risk factors | |||||||
| BMI, kg/m2 (Q1;Q3) | 25.5 (23.6;28.3) | 25.5 (23.6;28.5) | 25.5 (23.6;28.1) | 0.14 | |||
| Diabetes, n (%) | 94 (21.2) | 47 (32%) | 47 (16%) | p<10–4 | |||
| Hypertension, n (%) | 362 (82.8) | 107 (76.4) | 255 (85.9) | 0.020 | |||
| Total cholesterol, g/L (Q1;Q3) | 2.08 (1.72;2.38) | 1.45 (1.25;1.72) | 2.23 (2.00;2.47) | p<10–4 | |||
| LDL-c, g/L (Q1;Q3) | 1.25 (0.94;1.52) | 0.77 (0.61;1.03) | 1.39 (1.19;1.60) | p<10–4 | |||
| HDL-c, g/L (Q1;Q3) | 0.56 (0.46;0.66) | 0.47 (0.39;0.57) | 0.59 (0.50;0.68) | p<10–4 | |||
| Smoking, n (%) | 32 (7.2) | 6 (4.4) | 26 (8.7) | 0.117 | |||
| Prevalence of CHIP and mLOY | |||||||
| CHIP prevalence, n (%) | 201 (45.1) | 79 (53%) | 122 (41%) | 0.923 | |||
| Prevalence of CHIP with VAF ≥5% | 88 (19.7) | 30 (20.1) | 58 (19.5) | 0.069 | |||
| Subjects tested for mLOY, n | 220 | 97 | 123 | - | |||
| mLOY prevalence, n (%) | 83 (37.7) | 44 (45.4) | 39 (31.7) | 0.783 | |||
| CHIP(+) / mLOY(+) prevalence, n (%) | 39 (17.7) | 22 (22.7) | 17 (13.8) | 0.797 | |||
Data are expressed as numbers and frequency or median, first and third quartiles. For quantitative values, comparisons were made by linear regression of log values adjusted for age and sex. For qualitative parameters, comparisons were made by the fisher test. For each variable, results are expressed among patients with available value.