Skip to main content
. 2024 Nov 21;13(23):1932. doi: 10.3390/cells13231932

Figure 6.

Figure 6

Schematic overview of surface stiffness and cytotoxicity effects of MMA on gingival tissue. Dental resin materials containing methyl methacrylate (MMA) can release toxic substances, leading to gingival irritation and inflammation. This figure illustrates the relationship between surface stiffness and cytotoxicity in human gingival fibroblasts (HGF) exposed to increasing concentrations of MMA (5 mM, 7.5 mM, 10 mM) on 0.2 kPa and TCP substrates. As surface stiffness increases, cytotoxicity is elevated, suggesting a stiffness-dependent cytotoxic response to MMA exposure.