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. 1976 Sep 15;158(3):643–646. doi: 10.1042/bj1580643

Binding of diethylstilboestrol to deoxyribonucleic acid by rat liver microsomal fractions in vitro and in mouse foetal cells in culture.

G M Blackburn, M H Thompson, H W King
PMCID: PMC1164021  PMID: 985456

Abstract

Diethylstillboestrol, a synthetic and carcinogenic hormone, binds to DNA as a result of incubation with a liver microsomal preparation in vitro and on incubation with primary mouse foetal cells in culture. Enzymic digestion of DNA samples thus prepared gives several covalent deoxyribonucleoside-diethylstilboestrol products from the microsomal system. One of these is produced in small but significant yield in the tissue-culture system.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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