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. 1977 Apr 15;164(1):283–286. doi: 10.1042/bj1640283

Permeability of the liver cell membrane to quinolinate.

K R Elliott, C I Pogson, S A Smith
PMCID: PMC1164787  PMID: 880236

Abstract

Quinolinate was taken up by both rat and guinea-pig liver cells. Equilibrium was reached after approx. 20 min with rat cells, but guinea-pig cells had not achieved a steady state after 60 min. There was no evidence to suggest that quinolinate is rapidly metabolized by either species. The concentrations of quinolinate attained in rat and guinea-pig cells after short periods of incubation with 0.5 mM-quinolinate did not inhibit gluconeogenesis. These results raise further doubts as to the mechanism of quinolinate action in liver.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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