Table 5.
Variants associated with a relevant number of enrichment terms in Table 4 and, however, present low scores in the logistic regression models with LBW
| CHROM | POS | ID | GENE | SYMBOL | A1 | DESCRIPTION | ASSOCIATION | REFERENCES | OBSERVATIONS |
|---|---|---|---|---|---|---|---|---|---|
| 3 | 12348985 | rs17036328 | ENSG00000132170 | PPARG | T | Peroxisome proliferator activated receptor gamma. | Fasting blood insulin measurement. Body mass index. |
Black et al.40 | |
| 3 | 185793899 | rs4402960 | ENSG00000073792 | IGF2BP2 | G | Insulin like growth factor 2 mRNA binding protein 2. | Peak insulin response measurement. Type II diabetes mellitus. |
Ramos-LeviRodríguez et al.30 and Arnoriaga-Rodríguez et al.41 | |
| 6 | 7231610 | rs9379084 | ENSG00000124782 | RREB1 | A | Ras responsive element binding protein 1. | Appendicular lean mass. Birth weight. Diabetes mellitus. Fasting blood glucose measurement. Heel bone mineral density. Body height. HbA1c measurement. BMI-adjusted hip circumference. Body mass index. Parental genotype effect measurement. Type II diabetes mellitus. |
Warrington et al.21 | |
| 7 | 50723882 | rs6943153 | ENSG00000106070 | GRB10 | T | Growth factor receptor bound protein 10. | Fasting blood glucose measurement. | Holt and Siddle42 | Described as enigmatic regulator of insulin action. |
CHROM, Chromosome code; POS, Base-pair coordinate [GRCh38]; ID, Variant ID; A1, Counted allele in logistic regression.