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. 1985 Jun;140(Pt 4):551–563.

Granulated metrial gland cells in the lungs of mice in pregnancy and pseudopregnancy.

I Stewart
PMCID: PMC1165081  PMID: 4077696

Abstract

A study has been made, using light microscopy, of GMG cells in the lungs of pregnant mice and pseudopregnant mice with deciduomata. GMG cells are found in the lungs from Day 8 to Day 17 of pregnancy and are mainly located in the interalveolar septa. The temporal relationship between GMG cells in the lungs and GMG cells in the blood vessels of the decidua basalis and metrial gland suggests that the GMG cells in the lungs are migrants from the uterus. The presence of GMG cells in the lungs is considered in relation to the possibility that a site of functional importance to this cell type is the labyrinthine placenta. GMG cells are found in the uterine blood vessels and lungs of pseudopregnant mice with deciduomata. This finding suggests that the migration of GMG cells is under the influence of the mother rather than under the control of factors derived from the fetal allograft.

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Selected References

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  1. Bulmer D., Peel S. The demonstration of immunoglobulin in the metrial gland cells of the rat placenta. J Reprod Fertil. 1977 Jan;49(1):143–145. doi: 10.1530/jrf.0.0490143. [DOI] [PubMed] [Google Scholar]
  2. Dickson A. D., Krcek J. P. Numbers of metrial gland cells in the maternal placental supply and drainage vessels of Swiss Webster and C57B1 mice. J Anat. 1981 Dec;133(Pt 4):527–533. [PMC free article] [PubMed] [Google Scholar]
  3. Dickson A. D. Migration of metrial gland cells in the mouse. J Anat. 1980 Sep;131(Pt 2):255–262. [PMC free article] [PubMed] [Google Scholar]
  4. Finn C. A., McLaren A. A study of the early stages of implantation in mice. J Reprod Fertil. 1967 Apr;13(2):259–267. doi: 10.1530/jrf.0.0130259. [DOI] [PubMed] [Google Scholar]
  5. Jbara K., Stewart I. Granulated metrial gland cells in the uterus and labyrinthine placenta of inbred and outbred pregnancies in mice. J Anat. 1982 Sep;135(Pt 2):311–317. [PMC free article] [PubMed] [Google Scholar]
  6. Mitchell B. S., Craggs R., Peel S. Localisation of immunoglobulin (IgG) within the rat metrial gland. J Reprod Immunol. 1980 Nov;2(4):235–244. doi: 10.1016/0165-0378(80)90029-7. [DOI] [PubMed] [Google Scholar]
  7. Peel S., Stewart I. J., Bulmer D. Experimental evidence for the bone marrow origin of granulated metrial gland cells of the mouse uterus. Cell Tissue Res. 1983;233(3):647–656. doi: 10.1007/BF00212232. [DOI] [PubMed] [Google Scholar]
  8. Ruddell C. L. Embedding media for 1-2 micron sectioning. 2. Hydroxyethyl methacrylate combined with 2-butoxyethanol. Stain Technol. 1967 Sep;42(5):253–255. doi: 10.3109/10520296709115020. [DOI] [PubMed] [Google Scholar]
  9. Stewart I. A morphological study of granulated metrial gland cells and trophoblast cells in the labyrinthine placenta of the mouse. J Anat. 1984 Dec;139(Pt 4):627–638. [PMC free article] [PubMed] [Google Scholar]
  10. Stewart I. An investigation into the differentiation of granulated metrial gland cells in the early pregnant mouse uterus. J Anat. 1983 Aug;137(Pt 1):85–93. [PMC free article] [PubMed] [Google Scholar]
  11. Stewart I., Peel S. Granulated metrial gland cells at implantation sites of the pregnant mouse uterus. Anat Embryol (Berl) 1980;160(2):227–238. doi: 10.1007/BF00301863. [DOI] [PubMed] [Google Scholar]
  12. Stewart I., Peel S. The differentiation of the decidua and the distribution of metrial gland cells in the pregnant mouse uterus. Cell Tissue Res. 1978 Feb 14;187(1):167–179. doi: 10.1007/BF00220629. [DOI] [PubMed] [Google Scholar]
  13. Stewart I., Peel S. The structure and differentiation of granulated metrial gland cells of the pregnant mouse uterus. Cell Tissue Res. 1977 Nov 23;184(4):517–527. doi: 10.1007/BF00220975. [DOI] [PubMed] [Google Scholar]
  14. VELARDO J. T., DAWSON A. B., OLSEN A. G., HISAW F. L. Sequence of histological changes in the uterus and vagina of the rat during prolongation of pseudopregnancy associated with the presence of deciduomata. Am J Anat. 1953 Sep;93(2):272–305. doi: 10.1002/aja.1000930205. [DOI] [PubMed] [Google Scholar]

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