Abstract
Sprague-Dawley rats weighing 50 g were divided into two groups: (i) control, (ii) rats with tails bent in situ incorporating 7, 5 and 3 caudal vertebrae in the loop. Tails were radiographed weekly up to six weeks and a microradiographic and histological study undertaken on selected specimens. Results showed that the bones in the apex of the loop of the bent tail moved through their investing soft tissues towards the outer side of the bend, the joints became V-shaped and in tails bent acutely the epiphyses and metaphyses tilted. By six weeks the bones appeared bent with a thinner straight to convex shaft on the outer side and a thicker, more concave one on the inner side. The changes observed can be explained by taking into account (i) strain within the bone, (ii) altered growth and (iii) the translation of bones through their investing soft tissues. The results are consistent with the supposition that, on application of a continuous moderate stress, tension induces formation and pressure resorption of bone.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chamay A., Tschantz P. Mechanical influences in bone remodeling. Experimental research on Wolff's law. J Biomech. 1972 Mar;5(2):173–180. doi: 10.1016/0021-9290(72)90053-x. [DOI] [PubMed] [Google Scholar]
- Feik S. A., Storey E. Joint changes in transplanted caudal vertebrae. Pathology. 1982 Apr;14(2):139–147. doi: 10.3109/00313028209061287. [DOI] [PubMed] [Google Scholar]
- Feik S. A., Storey E. Remodelling of bone and bones: growth of normal and transplanted caudal vertebrae. J Anat. 1983 Jan;136(Pt 1):1–14. [PMC free article] [PubMed] [Google Scholar]
- Glucksmann A. The role of mechanical stresses in bone formation in vitro. J Anat. 1942 Apr;76(Pt 3):231–239. [PMC free article] [PubMed] [Google Scholar]
- Hammond R. H., Storey E. Measurement of growth and resorption of bone in rats fed meat diet. Calcif Tissue Res. 1970;4(4):291–304. doi: 10.1007/BF02279132. [DOI] [PubMed] [Google Scholar]
- Storey E., Feik S. A. Remodelling of bone and bones. Effects of altered mechanical stress on anlages. Br J Exp Pathol. 1982 Apr;63(2):184–193. [PMC free article] [PubMed] [Google Scholar]
- Storey E. Growth and remodeling of bone and bones. Am J Orthod. 1972 Aug;62(2):142–165. doi: 10.1016/0002-9416(72)90139-x. [DOI] [PubMed] [Google Scholar]
- Storey E. The nature of tooth movement. Am J Orthod. 1973 Mar;63(3):292–314. doi: 10.1016/0002-9416(73)90353-9. [DOI] [PubMed] [Google Scholar]