Abstract
The sialic acid content of highly purified human kininogen was found to be about 8.6 mol/mol(mol.wt. 50,000). The isoelectric point (pH 4.9 +/- 0.2) is much higher than that of bovine low-molecular-weight kininogen, but is close to that expected from the amino acid and sialic acid analyses.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- AMINOFF D. Methods for the quantitative estimation of N-acetylneuraminic acid and their application to hydrolysates of sialomucoids. Biochem J. 1961 Nov;81:384–392. doi: 10.1042/bj0810384. [DOI] [PMC free article] [PubMed] [Google Scholar]
- DAVIS B. J. DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS. Ann N Y Acad Sci. 1964 Dec 28;121:404–427. doi: 10.1111/j.1749-6632.1964.tb14213.x. [DOI] [PubMed] [Google Scholar]
- HABERMANN E., KLETT W., ROSENBUSCH G. PARTIELLE REINIGUNG UND EINIGE EIGENSCHAFTEN EINES KININOGENS AUS RINDERBLUT. Hoppe Seylers Z Physiol Chem. 1963;332:121–142. doi: 10.1515/bchm2.1963.332.1.121. [DOI] [PubMed] [Google Scholar]
- HABERMANN E. UBER PH-BEDINGTE MODIFIKATIONEN DES KININLIEFERNDEN ALPHA-GLOBULINS (KININOGEN) AUS RINDERSERUM UND DAS MOLEKULARGEWICHT VON KININOGEN I. Biochem Z. 1963 Jul 26;337:440–448. [PubMed] [Google Scholar]
- HAMBERG U. Bradykinin from total bovine plasma. Biochim Biophys Acta. 1959 Jul;34:135–146. doi: 10.1016/0006-3002(59)90241-0. [DOI] [PubMed] [Google Scholar]
- Habal F. M., Movat H. Z. Kininogens of human plasma. Res Commun Chem Pathol Pharmacol. 1972 Sep;4(2):477–486. [PubMed] [Google Scholar]
- Hamberg U. Kininogen in human plasma after fibrinolytic activation. Scand J Clin Lab Invest Suppl. 1969;107:37–47. [PubMed] [Google Scholar]
- Hamberg U., Tallberg T. Preparation of monospecific antiserum to human LMW kininogen using immunoadsorbents. J Immunol Methods. 1972 Nov;2(1):17–24. doi: 10.1016/0022-1759(72)90013-0. [DOI] [PubMed] [Google Scholar]
- Kato H., Suzuki T., Ikeda K., Hamaguchi K. Physicochemical properties of bovine kininogen-II. J Biochem. 1967 Nov;62(5):591–598. doi: 10.1093/oxfordjournals.jbchem.a128709. [DOI] [PubMed] [Google Scholar]
- Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
- Nagasawa S., Mizushima Y., Sato T., Iwanaga S., Suzuki T. Studies on the chemical nature of bovine bradykininogen: determinations of amino acid, carbohydrate, amino and carboxyl terminal residues. J Biochem. 1966 Dec;60(6):643–652. doi: 10.1093/oxfordjournals.jbchem.a128490. [DOI] [PubMed] [Google Scholar]
- Pierce J. V. Structural features of plasma kinins and kininogens. Fed Proc. 1968 Jan-Feb;27(1):52–57. [PubMed] [Google Scholar]
- Spragg J., Austen K. F. the preparation of human kininogen. II. Further characterization of purified human kininogen. J Immunol. 1971 Dec;107(6):1512–1519. [PubMed] [Google Scholar]
- Spragg J., Kaplan A. P., Austen K. F. The use of isoelectric focusing to study components of the human plasma kinin-forming system. Ann N Y Acad Sci. 1973 Jun 15;209:372–386. doi: 10.1111/j.1749-6632.1973.tb47541.x. [DOI] [PubMed] [Google Scholar]