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. 1975 Jan;146(1):127–131. doi: 10.1042/bj1460127

Inhibition by ricin of protein synthesis in vitro. Inhibition of the binding of elongation factor 2 and of adenosine diphosphate-ribosylated elongation factor 2 to ribosomes.

L Montanaro, S Sperti, A Mattioli, G Testoni, F Stirpe
PMCID: PMC1165282  PMID: 167711

Abstract

The binding of EF2 (elongation factor 2) and of ADP-ribosyl-EF 2 to rat liver ribosomes is inhibited by ricin. This result suggests that the native enzyme and its ADP-ribose derivative have the same or closely related binding sites on the ribosome. The inhibition by ricin of the binding of EF 2 to ribosomes is consistent with the previous observation that ricin affects EF 2-catalysed translocation during polypeptide chain elongation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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