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. 1975 May;147(2):249–251. doi: 10.1042/bj1470249

Decarboxylation of uroporphyrin by heating at atmospheric pressure.

T K With
PMCID: PMC1165437  PMID: 1180892

Abstract

Free uroporphyrin is decarboxylated by heating in the air to 150--200 degrees C. Complete decarboxylation occurs after heating to 200 degrees C for 5 min, with a yield of 66--75%. Heptacarboxylic porphyrin can be prepared with a yield of 40% by heating uroporphyrin to 150 degrees C for 60 min, and hexacarboxylic porphyrin with a yield of about 20% by heating to 150 degrees C for 2h.

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Selected References

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