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. 1975 May;147(2):335–341. doi: 10.1042/bj1470335

Ligand binding to ferrocytochrome c at high pH.

T A Moore, C Greenwood, M T Wilson
PMCID: PMC1165447  PMID: 241325

Abstract

Ferrocytochrome c has been shown to bind two molecules of CO at pH 14. The second CO is thought to be bound only when the cytochrome c molecule is denatured, and once bound appears to be spectrally silent. Insolubilization of native cytochrome c prevents the binding of the second CO molecule. A scheme is proposed to explain these observations based on evidence from static titrations and flash-photolysis experiments, use of carboxymethyl cytochrome c and insoluble cytochrome c, and use of cyanide instead of CO as a ligand.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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