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. 1975 Jun;147(3):605–607. doi: 10.1042/bj1470605

pH-dependence of 13C chemical shifts and 13C,H coupling constants in imidazole and L-histidine.

R E Wasylishen, G Tomlinson
PMCID: PMC1165488  PMID: 241331

Abstract

The pH-dependence of selected 13C chemical shifts reflects the state of ionization of the imidazole ring in both imidazole and L-histidine. Titration of the amino and carboxyl groups of histidine also perturbs the shifts. The coupling constants 1J (13C(2),H) and 1J (13C(5),H) for both compounds also vary with pH, but in L-histidine these constants are relatively insensitive to the titration of groups outside the imidazole ring.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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