Concerns have been raised about discrepancies in the methods and results between this article [1] and a related thesis by the first author [2]. In response, the first author stated that the discrepancies are due to errors in [2]. The first author also provided the underlying data for this article [S1–S9 Files] and additional information on the antibodies used in [1] (Table 1). The VEGFR2 antibody details were not clarified.
Table 1. Antibody details.
| Antibody | Description | Source | Catalogue number |
|---|---|---|---|
| IGF receptors | Mouse monoclonal antibody against human IGF-1 receptor | Thermo Fisher Scientific (Fremont, USA). | Biocare Medical CM 414 A, C |
| CD31 | Mouse monoclonal antibody against human CD31 | Thermo Fisher Scientific (Fremont, USA). | #MS-353-R7 |
A member of the Editorial Board reviewed the concerns and authors’ responses, and was satisfied with the responses, but noted that hematoxylin & eosin (H&E) staining is mentioned in the Materials and Methods in [1] but is not shown.
Supporting information
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References
- 1.Abd-Alhaseeb MM, Zaitone SA, Abou-El-Ela SH, Moustafa YM (2014) Olmesartan Potentiates the Anti-Angiogenic Effect of Sorafenib in Mice Bearing Ehrlich’s Ascites Carcinoma: Role of Angiotensin (1–7). PLoS ONE 9(1): e85891. 10.1371/journal.pone.0085891 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Abd-Alhaseeb El-Mahdy MM (2010) Anti-angiogenic effect of the AT1R blocker, Olmesartan, in addition to sorafenib in in-vivo and in-vitro models of cancer. PhD thesis, Suez Canal University [Google Scholar]
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Supplementary Materials
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