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. 1973 Dec;135(4):905–908. doi: 10.1042/bj1350905

Binding of oligosaccharides of hyaluronic acid to proteoglycans (Short Communication)

Timothy E Hardingham 1, Helen Muir 1
PMCID: PMC1165913  PMID: 4273187

Abstract

Oligosaccharides derived from hyaluronic acid were shown to inhibit proteoglycan–hyaluronic acid interaction, as measured in a viscometer. The relative inhibition increased with the size of the oligosaccharide and the results suggested that decasaccharides were the smallest fragments able to bind strongly to the proteoglycan.

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Selected References

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