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. 1974 Feb;137(2):217–221. doi: 10.1042/bj1370217

A low-molecular-weight protein cross-reacting with human liver N-acetyl-β-d-glucosaminidase

Mark Carroll 1, Donald Robinson 1
PMCID: PMC1166107  PMID: 4207386

Abstract

Antisera were raised to preparations of hexosaminidase isoenzymes A and B purified from human liver. Protein that cross-reacted with the liver hexosaminidase was detected by an antibody-consumption method. A cross-reacting protein with a low molecular weight (20000) was partially characterized and purified from control human liver. This protein is also present in the liver of patients with Tay–Sachs disease or with Sandhoff's disease. Hexosaminidases A and B gave an immunological reaction of partial identity with the low-molecular-weight protein. The possible identity of the low-molecular-weight cross-reacting protein as a subunit of hexosaminidase is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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