Table 5. Multifactorial analysis of the risk of elevated LDH, CRP, and D-Di levels on admission to the hospital.

* Adjusted for age and underlying disease. Using one-way and multifactorial regression analyses, P < 0.05 indicates statistical significance.

≧1: patient's lymphocyte count on admission ≧1 (10^9/L); <1: patient's lymphocyte count on admission <1 (10^9/L). Interaction term: groups A, B, C, and D of the target group.

LDH: lactate dehydrogenase; CRP: C-reactive protein; D-Di: D-dimer.

Variables	Crude OR (95%CI)	P1	Adjusted OR (95%CI)	P2
Elevated levels of LDH
Vaccination (reference: unvaccinated)
Vaccinated	0.860 (0.540 - 1.360)	0.520	0.920 (0.580 - 1.470)	0.734
immunity status (reference: <1)
≧1	0.640 (0.410 - 0.990)	0.045	0.670 (0.43 - 1.040)	0.075
Interaction term (reference: A)
B	1.244 (0.591 - 2.620)	0.565	1.237 (0.583 - 2.627)	0.580
C	0.607 (0.310 - 1.188)	0.145	0.697 (0.351 - 1.384)	0.302
D	1.105 (0.566 - 2.158)	0.770	1.135 (0.577 - 2.233)	0.713
Elevated levels of CRP
Vaccination (reference: unvaccinated)
Vaccinated	0.580 (0.360 - 0.940)	0.026	0.610 (0.370 - 0.990)	0.044
immunity status (reference: <1)
≧1	0.650 (0.420 - 1.010)	0.057	0.690 (0.440 - 1.090)	0.109
Interaction term (reference: A)
B	1.855 (0.834 - 4.127)	0.130	1.795 (0.804 - 4.008)	0.154
C	0.689 (0.348 - 1.362)	0.284	0.716 (0.358 - 1.433)	0.346
D	0.967 (0.488 - 1.914)	0.922	0.957 (0.482 - 1.900)	0.899
Elevated levels of D-Di
Vaccination (reference: unvaccinated)
Vaccinated	0.440 (0.260 - 0.760)	0.003	0.470 (0.270 - 0.810)	0.006
immunity status (reference: <1)
≧1	0.460 (0.290 - 0.750)	0.002	0.490 (0.300 - 0.810)	0.005
Interaction term (reference: A)
B	3.021 (1.164 - 7.839)	0.023	2.919 (1.117 - 7.626)	0.029
C	0.466 (0.229 - 0.948)	0.035	0.513 (0.249 - 1.060)	0.072
D	1.010 (0.489 - 2.088)	0.978	1.008 (0.484 - 2.098)	0.983