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. 2024 Dec 4;27(12):111437. doi: 10.1016/j.isci.2024.111437

Figure 3.

Figure 3

miR-532-3p influences the IC50 values of OXA and 5-Fu in vitro

(A) miR-1250-5p, miR-4772-5p, and miR-532-3p levels were upregulated in QBC939 cells following transient transfection.

(B) MiR-1250-5p, miR-4772-5p, and miR-532-3p levels were downregulated in FRH0201 cells following transient transfection.

(C and D) The IC50 values of OXA (C) and 5-Fu (D) in QBC939 cells.

(E andF) The IC50 values of OXA (E) and 5-Fu (F) in FRH0201 cells.

Data are represented as mean ± SD. n = 3, ∗∗p < 0.01, ∗∗∗p < 0.001, IC50 half inhibitory concentration, OXA oxaliplatin, 5-Fu 5-fluorouracil, NC negative control.