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. 2024 Dec 20;12:e18719. doi: 10.7717/peerj.18719

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© 2024 Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) qPCR for the expression of three model genes (METTL3, IGF2BP3 and YTHDC2). (B and C) Knockdown of METTL3 in SW1116 cells reduces the cellular wound healing rate (B) and the number of invading cells (C). (D and E) Overexpression of YTHDC2 did not significantly affect the migration (D) and invasion (E) ability of SW1116 cells. (F and G) Knockdown of IGF2BP3 significantly inhibited the wound healing rate (F) and the number of invading cells (G) in SW1116 cells All experimental data of independent triplicates were expressed as mean ± standard deviation. (**p < 0.01, ***p < 0.001, and ****p < 0.0001).