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. 1986 Aug;5(8):1991–1993. doi: 10.1002/j.1460-2075.1986.tb04454.x

Mating pheromone-like diffusible factor released by Schizosaccharomyces pombe

Yasuhisa Fukui 1, Yoshito Kaziro 1, Masayuki Yamamoto 1
PMCID: PMC1167068  PMID: 16453698

Abstract

We demonstrate that a diffusible factor is secreted by h cells of the fission yeast Schizosaccharomyces pombe, whose mating pheromones have not been described. This factor, tentatively named the h-factor, affects h+ S. pombe cells and induces their elongation under nitrogen-depleted conditions. Circumstantial evidence suggests its physiological significance in the mating process. Despite their sterility, h ras1 cells secrete this factor. However, h+ ras1 cells have apparently lost the ability to respond to it. This may suggest that the gene product of S. pombe ras1, a homologue of mammalian ras oncogenes, is involved in the mechanism for responding to mating pheromones.

Keywords: fission yeast, hfactor, ras1 mutants, sterility

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1991

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Selected References

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