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. 1974 Aug;142(2):441–443. doi: 10.1042/bj1420441

Peroxidatic oxidation of tyrosine to melanin in supernatant of crude mouse melanoma homogenates (Short Communication)

Ravindra P Patel 1,2,*, Milton R Okun 1,2, Leon M Edelstein 1,2, Nancy Cariglia 1,2
PMCID: PMC1168298  PMID: 4441386

Abstract

Peroxide-dependent enzymic oxidation of tyrosine to dopachrome and melanin was demonstrated in cell-free melanoma homogenates. Histochemical methods for distinguishing peroxidase activity from aerobic dopa (3,4-dihydroxyphenylalanine) oxidase activity are not reliable with cell-free preparations. Therefore the presence of peroxidase activity in such preparations precludes assay of cresolase activity of mammalian `tyrosinase'.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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