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. 1974 Dec;143(3):779–781. doi: 10.1042/bj1430779

The effect of systematic error on the accuracy of Michaelis constants and maximum velocities estimated by using the integrated Michaelis–Menten equation (Short Communication)

Peter F J Newman 1, Gordon L Atkins 1, Ian A Nimmo 1
PMCID: PMC1168449  PMID: 4462757

Abstract

Systematic errors in initial substrate concentration (s0), product concentration and reaction time give much larger errors in the Michaelis–Menten parameters unless s0 is treated as an unknown parameter. These errors are difficult to detect because the fitted curve deviates little from the data. The effect of non-enzymic reaction is also examined.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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