Abstract
Incubation of liver explants from second-trimester human foetuses with dexamethasone, glucagon or dibutyryl cyclic AMP (plus theophylline) increased the activity of liver cystathionase from unmeasurable or trace values to adult values. Simultaneous incubation with cycloheximide or actinomycin D inhibited this effect.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gaitonde M. K. A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids. Biochem J. 1967 Aug;104(2):627–633. doi: 10.1042/bj1040627. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gaull G., Sturman J. A., Räihä N. C. Development of mammalian sulfur metabolism: absence of cystathionase in human fetal tissues. Pediatr Res. 1972 Jun;6(6):538–547. doi: 10.1203/00006450-197206000-00002. [DOI] [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Pascal T. A., Gillam B. M., Gaull G. E. Cystathionase: immunochemical evidence for absence from human fetal liver. Pediatr Res. 1972 Oct;6(10):773–778. doi: 10.1203/00006450-197210000-00005. [DOI] [PubMed] [Google Scholar]
- ROSE W. C., WIXOM R. L. The amino acid requirements of man. XIII. The sparing effect of cystine on the methionine requirement. J Biol Chem. 1955 Oct;216(2):753–773. [PubMed] [Google Scholar]
- Schwartz A. L. Influence of glucagon, 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate and triamcinolone on the arginine synthetase system in perinatal rat liver. Biochem J. 1972 Jan;126(1):89–98. doi: 10.1042/bj1260089. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sturman J. A., Gaull G., Raiha N. C. Absence of cystathionase in human fetal liver: is cystine essential? Science. 1970 Jul 3;169(3940):74–76. doi: 10.1126/science.169.3940.74. [DOI] [PubMed] [Google Scholar]