Abstract
Axonal descending branches of stellate cells in the molecular layer of the cerebellar cortex of the rat were studied by means of Golgi and combined Golgi-ultrastructural methods. Special attention was paid to those branches from more superficially located cell bodies. With the Golgi method, it was observed that the number of axons from stellate cells forming pericellular baskets and 'pinceaux' increases as their cell bodies come to lie deeper in the layer. With the combined Golgi-ultrastructural method, it was verified that the synaptic contacts established by these axons are identical to those of axons from basket cells, either contacting Purkinje cell bodies or lying around the axon initial segments, where they establish septate-like junctions. This overlapping of axonal territories between stellate and basket cells is in accordance with the hypothesis that these interneurons, although situated at different levels of the cerebellar molecular layer, may be genetically identical cells. Their diversity of form would depend on the cellular microenvironment present at the time of differentiation.
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- Chan-Palay V., Palay S. L. The stellate cells of the rat's cerebellar cortex. Z Anat Entwicklungsgesch. 1972;136(2):224–248. doi: 10.1007/BF00519180. [DOI] [PubMed] [Google Scholar]
- Fairén A., Peters A., Saldanha J. A new procedure for examining Golgi impregnated neurons by light and electron microscopy. J Neurocytol. 1977 Jun;6(3):311–337. doi: 10.1007/BF01175194. [DOI] [PubMed] [Google Scholar]
- GRAY E. G. Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study. J Anat. 1959 Oct;93:420–433. [PMC free article] [PubMed] [Google Scholar]
- Gobel S. Axo-axonic septate junctions in the basket formations of the cat cerebellar cortex. J Cell Biol. 1971 Oct;51(1):328–333. doi: 10.1083/jcb.51.1.328. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rakic P. Extrinsic cytological determinants of basket and stellate cell dendritic pattern in the cerebellar molecular layer. J Comp Neurol. 1972 Nov;146(3):335–354. doi: 10.1002/cne.901460304. [DOI] [PubMed] [Google Scholar]
- Sotelo C., Llinás R. Specialized membrane junctions between neurons in the vertebrate cerebellar cortex. J Cell Biol. 1972 May;53(2):271–289. doi: 10.1083/jcb.53.2.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Winfield D. A., Brooke R. N., Sloper J. J., Powell T. P. A combined Golgi-electron microscopic study of the synapses made by the proximal axon and recurrent collaterals of a pyramidal cell in the somatic sensory cortex of the monkey. Neuroscience. 1981;6(7):1217–1230. doi: 10.1016/0306-4522(81)90183-4. [DOI] [PubMed] [Google Scholar]