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. 1975 Dec;152(3):709–712. doi: 10.1042/bj1520709

Role of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivo.

C J Eriksson, M Marselos, T Koivula
PMCID: PMC1172529  PMID: 1227509

Abstract

The activity of a high-Km aldehyde dehydrogenase in the liver cytosol was increased by phenobarbital induction. No corresponding increase in the oxidation rate of acetaldehyde in vivo was found, and it is concluded that cytosolic aldehyde dehydrogenase plays only a minor role in the oxidation of acetaldehyde during ethanol metabolism.

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Selected References

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