Skip to main content
Frontiers in Neurology logoLink to Frontiers in Neurology
. 2025 Jan 3;15:1540452. doi: 10.3389/fneur.2024.1540452

Corrigendum: Cipaglucosidase alfa plus miglustat: linking mechanism of action to clinical outcomes in late-onset Pompe disease

Barry J Byrne 1,*, Giancarlo Parenti 2,3, Benedikt Schoser 4, Ans T van der Ploeg 5, Hung Do 6, Brian Fox 7, Mitchell Goldman 7, Franklin K Johnson 7, Jia Kang 8, Nickita Mehta 7, John Mondick 9, M Osman Sheikh 7, Sheela Sitaraman Das 7, Steven Tuske 7, Jon Brudvig 7, Jill M Weimer 7, Tahseen Mozaffar 10
PMCID: PMC11738947  PMID: 39830206

In the published article, there was an error in Figure 13 as published. The error relates to the positive/negative value of some of the numbers on the axes for the lower MMT score and the GSGC total score in Figure 13A. For both lower MMT score and GSGC total score, the axis scale incorrectly read −3, −2, 1, 0, −1, −2, −3 from left to right, whereas the axis scale for lower MMT score should have been −3, −2, −1, 0, 1, 2, 3 and the axis scale for GSGC total score should have been 3, 2, 1, 0, −1, −2, −3. The corrected Figure 13 and its caption appear below.

Figure 13.

Figure 13

Change from baseline at week 52 of PROPEL—effect of cipaglucosidase alfa plus miglustat compared with alglucosidase alfa plus placebo in key efficacy outcomes. (A) Forest plot illustrating mean estimated treatment differences between cipaglucosidase alfa plus miglustat versus alglucosidase alfa plus placebo and corresponding 95% CIs are shown for the combined PROPEL study population for each outcome, with units as indicated on the x-axes. For all outcomes, right-sided directionality of treatment differences indicates favorable outcomes for cipaglucosidase alfa plus miglustat compared with alglucosidase alfa plus placebo. (B) The table shows baseline mean values and Week 52 CFBL values for cipaglucosidase alfa plus miglustat and alglucosidase alfa plus placebo. Shaded CFBL indicates nominally significant improvement (green) or nominally significant worsening (red) from baseline (i.e., the 95% CI does not include zero) within each treatment group. The p-values (two-tailed LS mean difference) shown in the far-right column are for the between-group treatment differences illustrated in the forest plot.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.


Articles from Frontiers in Neurology are provided here courtesy of Frontiers Media SA

RESOURCES