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. 2024 Dec 12;33(1):421. doi: 10.1016/j.ymthe.2024.12.005

A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer’s disease

João Fonseca-Gomes, Tiago Costa-Coelho, Mafalda Ferreira-Manso, Sara Inteiro-Oliveira, Sandra H Vaz, Nuno Alemãn-Serrano, Henrique Atalaia-Barbacena, Leonor Ribeiro-Rodrigues, Rita M Ramalho, Rui Pinto, Hugo Vicente Miranda, Sara R Tanqueiro, Carolina de Almeida-Borlido, Maria João Ramalho, Catarina Miranda-Lourenço, Rita F Belo, Catarina B Ferreira, Vera Neves, Diogo M Rombo, Ricardo Viais, Juzoh Umemori, Ivo C Martins, André Jerónimo-Santos, António Caetano, Nuno Manso, Petra Mäkinen, Mikael Marttinen, Mari Takalo, Michael Bremang, Ian Pike, Annakaisa Haapasalo, Joana A Loureiro, Maria Carmo Pereira, Nuno C Santos, Tiago F Outeiro, Miguel ARB Castanho, Adelaide Fernandes, Mikko Hiltunen, Carlos B Duarte, Eero Castrén, Alexandre de Mendonça, Ana M Sebastião, Tiago M Rodrigues , Maria José Diógenes ∗∗
PMCID: PMC11764483  PMID: 39672159

Main text

(Molecular Therapy 32, 3372–3401; October 2024)

After publication, the authors realized that Dr. Juzoh Umemori was mistakenly not considered an author of the paper. The corrected author list is now updated online.

All authors agreed to this change. Dr. Juzoh Umemori designed the plasmid "pFCK-CaMKIIα-TrkB-ICD-IRES-ZsGreen1" and supervised the construction process and lentivirus generation led by the first author. He also constructed empty vectors for NGS sequencing and managed the shipment of all viruses and plasmids. Furthermore, Dr. Umemori contributed to the manuscript by drafting sections on plasmid construction and lentivirus production, specifically the "LV plasmid generation" and "LV production and purification" sections. Additionally, the authors have also updated the acknowledgments section to include the following: "The service for sucrose purification and titer determination of the lentiviruses was provided by the Biomedicum Functional Genomics Unit at the Helsinki Institute of Life Science and Biocenter Finland at the University of Helsinki."

Contributor Information

Tiago M. Rodrigues, Email: tiago.rodrigues@iob.ch.

Maria José Diógenes, Email: diogenes@medicina.ulisboa.pt.


Articles from Molecular Therapy are provided here courtesy of The American Society of Gene & Cell Therapy

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