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. 1971 Feb;121(4):663–666. doi: 10.1042/bj1210663

Studies on type II glycogenosis. Effects of cortisone derivatives on acid α-glucosidase

E J Bourne 1, K Clarke 1, J B Pridham 1, J J M Rowe 1
PMCID: PMC1176643  PMID: 5286578

Abstract

Cortisone causes a marked increase in the activity of liver acid α-glucosidase 2h after injection into male Wistar rats. Studies on rat liver tissue slices, isolated lysosomes and cultured skin fibroblasts have demonstrated similar elevations of acid α-glucosidase activity after incubation with cortisone. Cortisone-treated human liver tissue, obtained by needle biopsy, also shows an increase in acid α-glucosidase activity. Neutral α-glucosidase activity was not stimulated by cortisone in vivo or in liver slices.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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