Skip to main content
Biochemical Journal logoLink to Biochemical Journal
. 1973 Apr;132(4):833–836. doi: 10.1042/bj1320833

The effect of cycloheximide on adipose-tissue clearing-factor lipase (Short Communication)

A Cryer 1, Barbara Foster 1, D R Wing 1, D S Robinson 1
PMCID: PMC1177659  PMID: 4721617

Abstract

The progressive increase in clearing-factor lipase activity that occurs during the incubation of adipose tissue from starved rats in an appropriate medium at 25°C is shown to occur in two stages. The first of these is not inhibited by cycloheximide, whereas the second is.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cunningham V. J., Robinson D. S. Clearing-factor lipase in adipose tissue. Distinction of different states of the enzyme and the possible role of the fat cell in the maintenance of tissue activity. Biochem J. 1969 Apr;112(2):203–209. doi: 10.1042/bj1120203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Garfinkel A. S., Schotz M. C. Separation of molecular species of lipoprotein lipase from adipose tissue. J Lipid Res. 1972 Jan;13(1):63–68. [PubMed] [Google Scholar]
  3. HERRERA M. G., RENOLD A. E. Hormonal effects on glycine metabolism in rat epididymal adipose tissue. Biochim Biophys Acta. 1960 Oct 21;44:165–167. doi: 10.1016/0006-3002(60)91536-5. [DOI] [PubMed] [Google Scholar]
  4. Patten R. L. The reciprocal regulation of lipoprotein lipase activity and hormone-sensitive lipase activity in rat adipocytes. J Biol Chem. 1970 Nov 10;245(21):5577–5584. [PubMed] [Google Scholar]
  5. ROBINSON D. S. THE CLEARING FACTOR LIPASE AND ITS ACTION IN THE TRANSPORT OF FATTY ACIDS BETWEEN THE BLOOD AND TISSUES. Adv Lipid Res. 1963;1:133–182. doi: 10.1016/b978-1-4831-9937-5.50010-7. [DOI] [PubMed] [Google Scholar]
  6. Robinson D. S., Wing D. R. Studies on tissue clearing factor lipase related to its role in the removal of lipoprotein triglyceride from the plasma. Biochem Soc Symp. 1971;(33):123–135. [PubMed] [Google Scholar]
  7. Salaman M. R., Robinson D. S. Clearing-factor lipase in adipose tissue. A medium in which the enzyme activity of tissue from starved rats increases in vitro. Biochem J. 1966 Jun;99(3):640–647. doi: 10.1042/bj0990640. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Schotz M. C., Garfinkel A. S. Effect of nutrition on species of lipoprotein lipase. Biochim Biophys Acta. 1972 Aug 11;270(4):472–478. doi: 10.1016/0005-2760(72)90112-9. [DOI] [PubMed] [Google Scholar]
  9. Stewart J. E., Schotz M. C. Studies on release of lipoprotein lipase activity from fat cells. J Biol Chem. 1971 Sep 25;246(18):5749–5753. [PubMed] [Google Scholar]
  10. Wing D. R., Robinson D. S. Clearing-factor lipase in adipose tissue. A possible role of adenosine 3',5'-(cyclic)-monophosphate in the regulation of its activity. Biochem J. 1968 Oct;109(5):841–849. doi: 10.1042/bj1090841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Wing D. R., Robinson D. S. Clearing-factor lipase in adipose tissue. Studies with puromycin and actinomycin. Biochem J. 1968 Feb;106(3):667–676. doi: 10.1042/bj1060667. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Wing D. R., Salaman M. R., Robinson D. S. Clearing-factor lipase in adipose tissue. Factors influencing the increase in enzyme activity produced on incubation of tissue from starved rats in vitro. Biochem J. 1966 Jun;99(3):648–656. doi: 10.1042/bj0990648. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES