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. 1973 Aug;134(4):1023–1029. doi: 10.1042/bj1341023

Quantitative characteristics of glutamate transport in rat liver mitochondria

Norah M Bradford 1, J D McGivan 1
PMCID: PMC1177911  PMID: 4762750

Abstract

1. The kinetics of glutamate transport into mitochondria were determined by using Bromocresol Purple to terminate the transport process. 2. Glutamate transport was found to have a Vmax. of 9.1nmol/min per mg of protein at pH6.9 and 20°C; the Km for glutamate was 4mm. 3. The rate of glutamate deamination in intact mitochondria was tenfold slower than in disrupted mitochondria. 4. These results suggest that glutamate deamination may be controlled by the rate of glutamate transport. Possible consequences of these findings are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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