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. 1972 Apr;127(2):369–373. doi: 10.1042/bj1270369

Further studies on the lipids of corynebacteria. The mannolipids of Corynebacterium aquaticum

G K Khuller 1, P J Brennan 1
PMCID: PMC1178597  PMID: 4342553

Abstract

1. The major free lipids of Corynebacterium aquaticum were characterized as dimannosyl diglyceride, monomannophosphoinositide and phosphatidylethanolamine. Bisphosphatidylglycerol and phosphatidylglycerol were also tentatively identified. 2. We regard this as the only well-documented case of an organism containing monomannophosphoinositide to the exclusion of dimannophosphoinositides and the higher homologues. 3. The co-existence of the two mannolipids in one organism is a distinctive feature. So also is the presence of phosphatidylethanolamine in a corynebacterium. 4. The monomannophosphoinositide apparently does not utilize phosphatidylinositol as a precursor, unlike the monomannophosphoinositide of Propionibacterium shermanii. CDP-diglyceride may be necessary for its synthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BALLOU C. E., LEE Y. C. THE STRUCTURE OF A MYOINOSITOL MANNOSIDE FROM MYCOBACTERIUM TUBERCULOSIS GLYCOLIPID. Biochemistry. 1964 May;3:682–685. doi: 10.1021/bi00893a014. [DOI] [PubMed] [Google Scholar]
  2. Brennan P. J., Lehane D. P. The phospholipids of corynebacteria. Lipids. 1971 Jun;6(6):401–409. doi: 10.1007/BF02531377. [DOI] [PubMed] [Google Scholar]
  3. Brennan P. J., Lehane D. P., Thomas D. W. Acylglucoses of the corynebacteria and mycobacteria. Eur J Biochem. 1970 Mar 1;13(1):117–123. doi: 10.1111/j.1432-1033.1970.tb00906.x. [DOI] [PubMed] [Google Scholar]
  4. Brennan P. J. Phosphoinositides of Corynebacterium xerosis. Biochem J. 1968 Aug;109(1):158–160. doi: 10.1042/bj1090158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Brennan P., Ballou C. E. Biosynthesis of mannophosphoinositides by Mycobacterium phlei. The family of dimannophosphoinositides. J Biol Chem. 1967 Jul 10;242(13):3046–3056. [PubMed] [Google Scholar]
  6. Brennan P., Ballou C. E. Phosphatidylmyoinositol monomannoside in Propionibacterium shermanii. Biochem Biophys Res Commun. 1968 Jan 11;30(1):69–75. doi: 10.1016/0006-291x(68)90714-6. [DOI] [PubMed] [Google Scholar]
  7. Hill D. L., Ballou C. E. Biosynthesis of mannophospholipids by Mycobacterium phlei. J Biol Chem. 1966 Feb 25;241(4):895–902. [PubMed] [Google Scholar]
  8. Ikawa M. Bacterial phosphatides and natural relationships. Bacteriol Rev. 1967 Mar;31(1):54–64. doi: 10.1128/br.31.1.54-64.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Khuller G. K., Subrahmanyam D. On the mannophosphoinositides of Mycobacterium 607. Experientia. 1968 Aug 15;24(8):851–852. doi: 10.1007/BF02144914. [DOI] [PubMed] [Google Scholar]
  10. LEE Y. C., BALLOU C. E. STRUCTURAL STUDIES ON THE MYO-INOSITOL MANNODIDES FROM THE GLYCOLIPIDS OF MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM PHLEI. J Biol Chem. 1964 May;239:1316–1327. [PubMed] [Google Scholar]
  11. Minnikin D. E., Abdolrahimzadeh H., Baddiley J. The interrelation of phosphatidylethanolamine and glycosyl diglycerides in bacterial membranes. Biochem J. 1971 Sep;124(2):447–448. doi: 10.1042/bj1240447. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Motomiya M., Mayama A., Fujimoto M., Sato H., Oka S. Chemistry and biology of phospholipids from an unclassified mycobacteria, P6. Chem Phys Lipids. 1969 Apr;3(2):159–167. doi: 10.1016/0009-3084(69)90007-3. [DOI] [PubMed] [Google Scholar]
  13. Prottey C., Ballou C. E. Diacyl myoinositol monomannoside from Propionibacterium shermanii. J Biol Chem. 1968 Dec 10;243(23):6196–6201. [PubMed] [Google Scholar]
  14. Shaw N. Bacterial glycolipids. Bacteriol Rev. 1970 Dec;34(4):365–377. doi: 10.1128/br.34.4.365-377.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Shaw N., Dinglinger F. The structure of an acylated inositol mannoside in the lipids of propionic acid bacteria. Biochem J. 1969 May;112(5):769–775. doi: 10.1042/bj1120769. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Shaw N., Stead D. A study of the lipid composition of Microbacterium thermosphactum as a guide to its taxonomy. J Appl Bacteriol. 1970 Sep;33(3):470–473. doi: 10.1111/j.1365-2672.1970.tb02222.x. [DOI] [PubMed] [Google Scholar]
  17. Shaw N. The detection of lipids on thin-layer chromatograms with the periodate-Schiff reagents. Biochim Biophys Acta. 1968 Oct 22;164(2):435–436. doi: 10.1016/0005-2760(68)90171-9. [DOI] [PubMed] [Google Scholar]
  18. Subrahmanyam D., Singhvi D. R. Phosphatide antigens of mycobacteria. Proc Soc Exp Biol Med. 1965 Oct;120(1):102–105. doi: 10.3181/00379727-120-30456. [DOI] [PubMed] [Google Scholar]
  19. TREVELYAN W. E., PROCTER D. P., HARRISON J. S. Detection of sugars on paper chromatograms. Nature. 1950 Sep 9;166(4219):444–445. doi: 10.1038/166444b0. [DOI] [PubMed] [Google Scholar]

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