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. 1972 Apr;127(3):503–508. doi: 10.1042/bj1270503

The molecular weights of two forms of carbamoyl phosphate synthase from rat liver

R Virden 1
PMCID: PMC1178690  PMID: 5076192

Abstract

1. N-Acetylglutamate-dependent carbamoyl phosphate synthase from rat liver was centrifuged in sucrose density gradients. The concentration-dependence of s was consistent with a chemical equilibrium existing between the 11S and 7.5S forms of the enzyme. 2. Under conditions favouring the 11S form, the properties of the enzyme in ultra-short-column equilibrium experiments suggest a molecular weight of 316000±42000 for the 11S form. 3. Under conditions favouring the 7.5S form, high-speed equilibrium-sedimentation measurements gave a value of 160000±10000 as the molecular weight of the 7.5S form of the enzyme.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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