Fig. 3.
Comparison of cancer characteristics between R337H and non-R337H carriers by sex. A) Ages at last follow-up of male and female individuals carrying TP53 R337H or non-R337H variants. B) Ages of male and female individuals at first tumor diagnosis (Wilcoxon tests); C) Kaplan–Meier curves showing the cumulative risks of male and female individuals (R337H and non-R337H carriers) of developing a first tumor (pairwise log-rank tests; FDR adjusted p-values); D) Tumor profile in male and female individuals carrying TP53 R337H or non-R337H variants; E) Temporal patterns of tumor occurrence in male and female individuals (Wilcoxon tests). P-value representation: “∗”: p < 0.05; “∗∗”: p < 0.01; “∗∗∗∗”: p < 0.0001; ns: not significant.
