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. 1970 May;117(4):641–660. doi: 10.1042/bj1170641

The amino acid sequences of the Fd fragments of two human γ heavy chains

E M Press 1, N M Hogg 1
PMCID: PMC1179015  PMID: 5449120

Abstract

The amino acid sequences of the Fd fragments of two human pathological immunoglobulins of the immunoglobulin G1 class are reported. Comparison of the two sequences shows that the heavy-chain variable regions are similar in length to those of the light chains. The existence of heavy chain variable region subgroups is also deduced, from a comparison of these two sequences with those of another γ 1 chain, Eu, a μ chain, Ou, and the partial sequence of a fourth γ 1 chain, Ste. Carbohydrate has been found to be linked to an aspartic acid residue in the variable region of one of the γ 1 chains, Cor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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