PLANT BIOLOGY. For the article “The power of chemical genomics to study the link between endomembrane system components and the gravitropic response,” by Marci Surpin, Marcela Rojas-Pierce, Clay Carter, Glenn R. Hicks, Jacob Vasquez, and Natasha V. Raikhel, which appeared in issue 13, March 29, 2005, of Proc. Natl. Acad. Sci. USA (102, 4902-4907; first published March 16, 2005; 10.1073/pnas.0500222102), the authors note that in Table 1, the concentrations are incorrectly presented as “M” instead of “μM,” due to a printer's error. The corrected table appears below. In addition, the authors note the last sentence of the Fig. 3 legend, “Chemical structures are shown in Table 1,” should be removed. The structures now appear online in Table 2, which is published as supporting information on the PNAS web site. These errors do not affect the conclusions of the article.
Table 1. Potency of chemicals and reversibility of their effects.
| Inhibition of gravitropism, IC50*
|
Inhibition of growth
|
Inhibition of hypocotyl bending
|
Vacuolar effects
|
||||
|---|---|---|---|---|---|---|---|
| Chemical | Hypocotyl | Root | Hypocotyl length†‡ | Root length†‡ | Inducible | Reversible | Reversible |
| 2,4D | NA | 0.02 μM | NA | 96.8 (0.02 μM) | ND | ND | ND |
| 5403629 | 0.08 μM | 0.2 μM | 90.4 (0.1 μM) | 60 (0.3 μM) | Yes | Yes | Yes |
| 5271050 | 2 μM | NA | 88.7 (2 μM) | NA | Yes | Yes | No |
| 5850247 | 0.2 μM | 0.3 μM | 93.8 (0.3 μM) | 98.8 (0.3 μM) | Yes | No | Yes |
| 6220480 | NA | 8 μM | NA | 21.8 (10 μM) | NA | NA | Yes |
NA, not applicable, because chemical has little or no effect on gravitropism. ND, not determined.
Estimated concentration resulting in 50% inhibition after 24-h gravistimulation.
Lengths are reported as a percentage of the untreated controls.
Length measurements performed at the concentrations indicated.