Author Correction: SGF29 nuclear condensates reinforce cellular aging

Correction to: Cell Discovery 10.1038/s41421-023-00602-7, published online 07 November 2023

In this article, we identified an oversight in Fig. 5g¹, where the red and green channel images were inadvertently reversed. Also, Supplementary Fig. S7d contained an oversight with the selection of an atypical nucleus for EGFP-SGF29-WT group.

Incorrect Figure 5

Fig. 5. Identification of SGF29 interacting proteins sensitive to condensate perturbation.

a Flow chart of the mass spectrometry strategy for the identification of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) interacting proteins. Flag-EGFP was used as a control. b Shared and specific interacting proteins of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) identified by mass spectrometry. c Chord diagrams showing the enriched pathways of shared interaction partners of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) (left) and those of specific protein interaction partners of EGFP-SGF29-WT (right). d Co-IP analysis showing the interaction between indicated proteins and EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) in hMPCs. e Immunofluorescence staining of MED4 in hMPCs transduced with lentiviruses expressing either EGFP, EGFPSGF29-WT (WT) or EGFP-SGF29-R207P (R207P). Left, representative images. Scale bar, 10 μm. Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. f Immunofluorescence staining of Pol II S2 and SGF29 in senescent hMPCs. Left, representative images. Scale bars, 10 μm and 5 μm (zoomed-in image). Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. g Immunofluorescence staining of SP1 and SGF29 in senescent hMPCs. Left, representative images. Scale bars, 10 μm and 5 μm (zoomed-in image). Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. h Coomassie blue staining of purified recombinant SGF29-C-D194A and SGF29-C-R207P after being resolved on SDS-PAGE. i Pelleting assay show that SGF29-C-D194A and SGF29-C-R207P interact with MED4 and SP1.

Correct Figure 5

Fig. 5. Identification of SGF29 interacting proteins sensitive to condensate perturbation.

a Flow chart of the mass spectrometry strategy for the identification of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) interacting proteins. Flag-EGFP was used as a control. b Shared and specific interacting proteins of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) identified by mass spectrometry. c Chord diagrams showing the enriched pathways of shared interaction partners of EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) (left) and those of specific protein interaction partners of EGFP-SGF29-WT (right). d Co-IP analysis showing the interaction between indicated proteins and EGFP-SGF29-WT (WT) and EGFP-SGF29-R207P (R207P) in hMPCs. e Immunofluorescence staining of MED4 in hMPCs transduced with lentiviruses expressing either EGFP, EGFPSGF29-WT (WT) or EGFP-SGF29-R207P (R207P). Left, representative images. Scale bar, 10 μm. Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. f Immunofluorescence staining of Pol II S2 and SGF29 in senescent hMPCs. Left, representative images. Scale bars, 10 μm and 5 μm (zoomed-in image). Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. g Immunofluorescence staining of SP1 and SGF29 in senescent hMPCs. Left, representative images. Scale bars, 10 μm and 5 μm (zoomed-in image). Right, quantification of the fluorescence intensity along the line embedded the image following the arrow direction. h Coomassie blue staining of purified recombinant SGF29-C-D194A and SGF29-C-R207P after being resolved on SDS-PAGE. i Pelleting assay show that SGF29-C-D194A and SGF29-C-R207P interact with MED4 and SP1.

While these issues do not impact the results or conclusions, we are committed to the highest standards of publication integrity. The original figure and Supplementary figures have been corrected. We apologize for any inconvenience that it may have caused.

Supplementary information

The online version contains supplementary material available at 10.1038/s41421-025-00773-5.