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. 1978 Dec 1;175(3):1033–1042. doi: 10.1042/bj1751033

The structure of C-polysaccharide from the walls of Streptococcus pneumoniae.

I R Poxton, E Tarelli, J Baddiley
PMCID: PMC1186166  PMID: 33662

Abstract

The well-known immologically active component of pneumococci, C-polysaccharide, is a teichoic acid that can be isolated from the cell walls and purified by Sephadex and ion-exchange chromatography. Further details of the structure of C-teichoic acid were established by chemical degradation, including hydrolysis in acid and alkali, treatment with HF, periodate oxidation and methylation. In addition, the use of 13C n.m.r. has confirmed some of these structural features and resulted in a proposal for the order of substituents, the location of positions of substitution and the configuration of anomeric centres in the repeating unit of the polymer.

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Selected References

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