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. 1979 Mar 1;177(3):801–808. doi: 10.1042/bj1770801

Aminotripeptidase, a cytosol enzyme from rabbit intestinal mucosa.

C Doumeng, S Maroux
PMCID: PMC1186443  PMID: 109082

Abstract

Aminotripeptidase, a cytosol enzyme from rabbit intestinal mucosa, was purified to homogeneity. The pure enzyme is a glycoprotein containing a very small amount of sugar. It is composed of only one subunit of 50,000 mol. wt. and possesses 1 zinc atom per molecule. Its specificity is primarily directed towards tripeptides with an N-terminal proline residue. However, the enzyme is also able to hydrolyse other tripeptides, except those with either a charged amino acid in the N-terminal position or a proline residue in the second position. The purified aminotripeptidase accounts for almost all the tripeptidase activity of the soluble fraction from intestinal mucosa.

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Selected References

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