Skip to main content
NCBI home page
Biochemical Journal logoLink to Biochemical Journal
. 1979 Jan 15;178(1):245–248. doi: 10.1042/bj1780245

Involvement of cytoskeletal structures in nerve-growth-factor-mediated induction of ornithine decarboxylase.

J Lakshmanan
PMCID: PMC1186504  PMID: 571277

Abstract

Induction of ornithine decarboxylase elicited in response to nerve-growth factor in target organs is greatly decreased by preincubation of these tissues with cytoskeletal poisons such as vinblastine, diamide, cytochalasin B and colchicine. These results are interpreted as evidence for the involvement of receptor-associated cytoskeletal structures in mediating the nerve-growth-factor-specific induction of ornithine decarboxylase.

Full text

PDF
245

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BIGGERS J. D., GWATKIN R. B., HEYNER S. Growth of embryonic avian and mammalian tibiae on a relatively simple chemically defined medium. Exp Cell Res. 1961 Oct;25:41–58. doi: 10.1016/0014-4827(61)90305-6. [DOI] [PubMed] [Google Scholar]
  2. Bocchini V., Angeletti P. U. The nerve growth factor: purification as a 30,000-molecular-weight protein. Proc Natl Acad Sci U S A. 1969 Oct;64(2):787–794. doi: 10.1073/pnas.64.2.787. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bryan J. Definition of three classes of binding sites in isolated microtubule crystals. Biochemistry. 1972 Jul 4;11(14):2611–2616. doi: 10.1021/bi00764a010. [DOI] [PubMed] [Google Scholar]
  4. Chen K., Heller J., Canellakis E. S. Studies on the regulation of ornithine decarboxylase activity by the microtubules: the effect of colchicine and vinblastine. Biochem Biophys Res Commun. 1976 Jan 26;68(2):401–408. doi: 10.1016/0006-291x(76)91159-1. [DOI] [PubMed] [Google Scholar]
  5. Edelman G. M. Surface modulation in cell recognition and cell growth. Science. 1976 Apr 16;192(4236):218–226. doi: 10.1126/science.769162. [DOI] [PubMed] [Google Scholar]
  6. Estridge M. Polypeptides similar to the alpha and beta subunits of tubulin are exposed on the neuronal surface. Nature. 1977 Jul 7;268(5615):60–63. doi: 10.1038/268060a0. [DOI] [PubMed] [Google Scholar]
  7. Giller E. L., Jr, Schrier B. K., Shainberg A., Fisk H. R., Nelson P. G. Choline acetyltransferase activity is increased in combined cultures of spinal cord and muscle cells from mice. Science. 1973 Nov 9;182(4112):588–589. doi: 10.1126/science.182.4112.588. [DOI] [PubMed] [Google Scholar]
  8. Helfand S. L., Riopelle R. J., Wessells N. K. Non-equivalence of conditioned medium and nerve growth factor for sympathetic, parasympathetic, and sensory neurons. Exp Cell Res. 1978 Apr;113(1):39–45. doi: 10.1016/0014-4827(78)90085-x. [DOI] [PubMed] [Google Scholar]
  9. Jänne J., Pösö H., Raina A. Polyamines in rapid growth and cancer. Biochim Biophys Acta. 1978 Apr 6;473(3-4):241–293. doi: 10.1016/0304-419x(78)90015-x. [DOI] [PubMed] [Google Scholar]
  10. Levi-Montalcini R., Angeletti P. U. Nerve growth factor. Physiol Rev. 1968 Jul;48(3):534–569. doi: 10.1152/physrev.1968.48.3.534. [DOI] [PubMed] [Google Scholar]
  11. Levi-Montalcini R., Revoltella R., Calissano P. Microtubule proteins in the nerve growth factor mediated response. Interaction between the nerve growth factor and its target cells. Recent Prog Horm Res. 1974;30(0):635–669. doi: 10.1016/b978-0-12-571130-2.50021-3. [DOI] [PubMed] [Google Scholar]
  12. Levi-Montalcini R. The nerve growth factor: its mode of action on sensory and sympathetic nerve cells. Harvey Lect. 1966;60:217–259. [PubMed] [Google Scholar]
  13. Lewis M. E., Lakshmanan J., Nagaiah K., Macdonnell P. C., Guroff G. Nerve growth factor increases activity of ornithine decarboxylase in rat brain. Proc Natl Acad Sci U S A. 1978 Feb;75(2):1021–1023. doi: 10.1073/pnas.75.2.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. MacDonnell P. C., Nagaiah K., Lakshmanan J., Guroff G. Nerve growth factor increases activity of ornithine decarboxylase in superior cervical ganglia of young rats. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4681–4684. doi: 10.1073/pnas.74.10.4681. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Marantz R., Shelanski M. L. Structure of microtubular crystals induced by vinblastine in vitro. J Cell Biol. 1970 Jan;44(1):234–238. doi: 10.1083/jcb.44.1.234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Margolis R. L., Wilson L. Addition of colchicine--tubulin complex to microtubule ends: the mechanism of substoichiometric colchicine poisoning. Proc Natl Acad Sci U S A. 1977 Aug;74(8):3466–3470. doi: 10.1073/pnas.74.8.3466. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Mellon M. G., Rebhun L. I. Sulfhydryls and the in vitro polymerization of tubulin. J Cell Biol. 1976 Jul;70(1):226–238. doi: 10.1083/jcb.70.1.226. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Monard D., Stockel K., Goodman R., Thoenen H. Distinction between nerve growth factor anf glial factor. Nature. 1975 Dec 4;258(5534):444–445. doi: 10.1038/258444a0. [DOI] [PubMed] [Google Scholar]
  19. Nicolson G. L. Transmembrane control of the receptors on normal and tumor cells. I. Cytoplasmic influence over surface components. Biochim Biophys Acta. 1976 Apr 13;457(1):57–108. doi: 10.1016/0304-4157(76)90014-9. [DOI] [PubMed] [Google Scholar]
  20. O'Brien T. G., Simsiman R. C., Boutwell R. K. The effect of colchicine on the induction of ornithine decarboxylase by 12-O-tetradecanoyl-phorbol-13-acetate. Cancer Res. 1976 Oct;36(10):3766–3770. [PubMed] [Google Scholar]
  21. Oliver J. M., Albertini D. F., Berlin R. D. Effects of glutathione-oxidizing agents on microtubule assembly and microtubule-dependent surface properties of human neutrophils. J Cell Biol. 1976 Dec;71(3):921–932. doi: 10.1083/jcb.71.3.921. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Schubert D., LaCorbiere M., Whitlock C., Stallcup W. Alterations in the surface properties of cells responsive to nerve growth factor. Nature. 1978 Jun 29;273(5665):718–723. doi: 10.1038/273718a0. [DOI] [PubMed] [Google Scholar]
  23. Stastny M., Cohen S. Epidermal growth factor. IV. The induction of ornithine decarboxylase. Biochim Biophys Acta. 1970 Apr 15;204(2):578–589. [PubMed] [Google Scholar]
  24. Varon S. Nerve growth factor and its mode of action. Exp Neurol. 1975 Sep;48(3 Pt 2):75–92. doi: 10.1016/0014-4886(75)90172-7. [DOI] [PubMed] [Google Scholar]
  25. Wessells N. K., Spooner B. S., Ash J. F., Bradley M. O., Luduena M. A., Taylor E. L., Wrenn J. T., Yamada K. Microfilaments in cellular and developmental processes. Science. 1971 Jan 15;171(3967):135–143. doi: 10.1126/science.171.3967.135. [DOI] [PubMed] [Google Scholar]
  26. Wilson L., Friedkin M. The biochemical events of mitosis. II. The in vivo and in vitro binding of colchicine in grasshopper embryos and its possible relation to inhibition of mitosis. Biochemistry. 1967 Oct;6(10):3126–3135. doi: 10.1021/bi00862a021. [DOI] [PubMed] [Google Scholar]
  27. de Petris S. Concanavalin A receptors, immunoglobulins, and theta antigen of the lymphocyte surface. Interactions with concanavalin A and with Cytoplasmic structures. J Cell Biol. 1975 Apr;65(1):123–146. doi: 10.1083/jcb.65.1.123. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES