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. 1979 Feb 15;178(2):497–500. doi: 10.1042/bj1780497

Fatty acid stimulation of membrane phosphatidylinositol hydrolysis by brain phosphatidylinositol phosphodiesterase.

R F Irvine, A J Letcher, R M Dawson
PMCID: PMC1186539  PMID: 220968

Abstract

The hydrolysis of membrane-bound phosphatidylinositol in rat liver microsomal fraction by the soluble phosphatidylinositol phosphodiesterase from rat brain was markedly stimulated by oleic acid or arachidonic acid. The stimulation did not require added calcium, although it was abolished by EDTA. Lysophosphatidylcholine also totally suppressed the stimulation. A possible role for the fatty acid content of a membrane in controlling phosphatidylinositol turnover is suggested.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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