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. 1968 Nov;110(1):105–110. doi: 10.1042/bj1100105

The carnitine-independent oxidation of palmitate plus malate by moth flight-muscle mitochondria

Edmund Stevenson 1
PMCID: PMC1187114  PMID: 5722681

Abstract

Mitochondria isolated from the flight muscle of the southern armyworm moth, Prodenia eridania, can oxidize palmitate+malate very rapidly. Added carnitine had no effect on the rate of oxidation of palmitate+malate by flight-muscle mitochondria from two species of moths, and carnitine palmitoyltransferase could not be detected in Prodenia by direct assay. Palmitoylcarnitine was not oxidized by moth mitochondria, but when added in low concentrations it reversibly suppressed the oxidation of palmitate. The evidence indicates that carnitine is not involved in fatty acid degradation by moth flight muscle. Added thiols, including CoA, also suppressed palmitate+malate oxidation. An ATP-dependent fatty acyl-CoA synthetase is present in moth mitochondria.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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