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. 1969 Feb;111(3):309–315. doi: 10.1042/bj1110309

Studies in the enzymology of glutathione metabolism in human erythrocytes

R C Jackson 1
PMCID: PMC1187513  PMID: 4388010

Abstract

Spectrophotometric assay methods are described for glutathione synthetase, γ-glutamylcysteine synthetase and γ-glutamyl transpeptidase of erythrocytes. The contents of these enzymes in normal human erythrocytes are reported. Erythrocyte glutathione synthetase is inhibited by ADP; this inhibition is competitive with respect to ATP. γ-Glutamylcysteine synthetase is subject to feedback inhibition by GSH, and is also inhibited by NADH, and to a lesser extent by NAD+ and NADPH. This enzyme is irreversibly inactivated by cysteamine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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