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. 1997 Oct;61(4):312–314.

Reduced concentrations of apolipoproteins B-100 and A-I in serum from cows with retained placenta.

S Oikawa 1, N Katoh 1
PMCID: PMC1189428  PMID: 9342458

Abstract

The purpose of the present study was to evaluate apolipoprotein B-100 and A-I concentrations in cows with retained placenta. Animals used were cows with retained placenta alone (n = 10), those with both retained placenta and ketosis (n = 7), and controls (n = 10). Apolipoprotein B-100 concentrations at 2 to 4 d after parturition were significantly (P < 0.01) decreased in cows with retained placenta alone (mean +/- SD, 0.084 +/- 0.029 mg/ML of serum) when compared with those in control cows (0.154 +/- 0.022 mg/mL). Apolipoprotein A-I concentrations (0.713 +/- 0.177 mg/ML) were also significantly (P < 0.05) lower than those of controls (0.895 +/- 0.159 mg/mL). These decreases were more distinct for apolipoproteins B-100 (55% of controls) than A-I concentrations (80% of controls). Concentrations of apolipoprotein B-100 (0.071 +/- 0.032 mg/mL; P < 0.01) and A-I (0.708 +/- 0.189 mg/mL; P < 0.05) in the cows with both retained placenta and ketosis were also reduced, when compared with values in controls. Other than apolipoproteins, cows with retained placenta alone had significantly (P < 0.01) higher serum nonesterified fatty acids, and lower triglyceride concentrations. Significantly (P < 0.01) higher nonesterified fatty acids and lower triglyceride concentrations were similarly observed in cows with both retained placenta and ketosis.

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Selected References

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  1. Erb H. N., Grohn Y. T. Epidemiology of metabolic disorders in the periparturient dairy cow. J Dairy Sci. 1988 Sep;71(9):2557–2571. doi: 10.3168/jds.S0022-0302(88)79845-8. [DOI] [PubMed] [Google Scholar]
  2. Erb H. N., Smith R. D., Hillman R. B., Powers P. A., Smith M. C., White M. E., Pearson E. G. Rates of diagnosis of six diseases of Holstein cows during 15-day and 21-day intervals. Am J Vet Res. 1984 Feb;45(2):333–335. [PubMed] [Google Scholar]
  3. Gerloff B. J., Herdt T. H., Emery R. S. Relationship of hepatic lipidosis to health and performance in dairy cattle. J Am Vet Med Assoc. 1986 Apr 15;188(8):845–850. [PubMed] [Google Scholar]
  4. Grummer R. R. Etiology of lipid-related metabolic disorders in periparturient dairy cows. J Dairy Sci. 1993 Dec;76(12):3882–3896. doi: 10.3168/jds.S0022-0302(93)77729-2. [DOI] [PubMed] [Google Scholar]
  5. Gröhn Y., Lindberg L. A., Bruss M. L., Farver T. B. Fatty infiltration of liver in spontaneously ketotic dairy cows. J Dairy Sci. 1983 Nov;66(11):2320–2328. doi: 10.3168/jds.S0022-0302(83)82088-8. [DOI] [PubMed] [Google Scholar]
  6. Herdt T. H. Fatty liver in dairy cows. Vet Clin North Am Food Anim Pract. 1988 Jul;4(2):269–287. doi: 10.1016/s0749-0720(15)31048-3. [DOI] [PubMed] [Google Scholar]
  7. Herdt T. H., Liesman J. S., Gerloff B. J., Emery R. S. Reduction of serum triacylglycerol-rich lipoprotein concentrations in cows with hepatic lipidosis. Am J Vet Res. 1983 Feb;44(2):293–296. [PubMed] [Google Scholar]
  8. Holtenius P. Hormonal regulation related to the development of fatty liver and ketosis. Acta Vet Scand Suppl. 1993;89:55–60. [PubMed] [Google Scholar]
  9. KRONFELD D. S. PLASMA NON-ESTERIFIED FATTY ACID CONCENTRATIONS IN THE DAIRY COW: RESPONSES TO NUTRITIONAL AND HORMONAL STIMULI, AND SIGNIFICANCE IN KETOSIS. Vet Rec. 1965 Jan 9;77:30–35. [PubMed] [Google Scholar]
  10. Katoh N., Minoura S., Uchida E., Takahashi K. Effect of estradiol administration and subsequent nonfeeding on liver estrogen receptor, serum apolipoprotein B-100, and serum triglycerides concentrations in steers. Am J Vet Res. 1993 Sep;54(9):1476–1482. [PubMed] [Google Scholar]
  11. Marcos E., Mazur A., Cardot P., Rayssiguier Y. Serum apolipoproteins B and A-I and naturally occurring fatty liver in dairy cows. Lipids. 1990 Sep;25(9):575–577. doi: 10.1007/BF02537168. [DOI] [PubMed] [Google Scholar]
  12. Markusfeld O. Factors responsible for post parturient metritis in dairy cattle. Vet Rec. 1984 Jun 2;114(22):539–542. doi: 10.1136/vr.114.22.539. [DOI] [PubMed] [Google Scholar]
  13. Markusfeld O. Periparturient traits in seven high dairy herds. Incidence rates, association with parity, and interrelationships among traits. J Dairy Sci. 1987 Jan;70(1):158–166. doi: 10.3168/jds.S0022-0302(87)79990-1. [DOI] [PubMed] [Google Scholar]
  14. Morrow D. A. Fat cow syndrome. J Dairy Sci. 1976 Sep;59(9):1625–1629. doi: 10.3168/jds.S0022-0302(76)84415-3. [DOI] [PubMed] [Google Scholar]
  15. Morrow D. A., Hillman D., Dade A. W., Kitchen Y. Clinical investigation of a dairy herd with the fat cow syndrome. J Am Vet Med Assoc. 1979 Jan 15;174(2):161–167. [PubMed] [Google Scholar]
  16. Oikawa S., Katoh N., Itoh H., Miyamoto T., Konno M., Kajita T. Decreased serum apolipoprotein A-I concentrations in cows infected with Salmonella typhimurium. Can J Vet Res. 1997 Jul;61(3):182–186. [PMC free article] [PubMed] [Google Scholar]
  17. Oikawa S., Katoh N., Kawawa F., Ono Y. Decreased serum apolipoprotein B-100 and A-I concentrations in cows with ketosis and left displacement of the abomasum. Am J Vet Res. 1997 Feb;58(2):121–125. [PubMed] [Google Scholar]
  18. Rayssiguier Y., Mazur A., Gueux E., Reid I. M., Roberts C. J. Plasma lipoproteins and fatty liver in dairy cows. Res Vet Sci. 1988 Nov;45(3):389–393. [PubMed] [Google Scholar]
  19. Reid I. M., Roberts C. J., Manston R. Fatty liver and infertility in high-yielding dairy cows. Vet Rec. 1979 Jan 27;104(4):75–76. doi: 10.1136/vr.104.4.75. [DOI] [PubMed] [Google Scholar]
  20. Stevenson J. S., Call E. P. Reproductive disorders in the periparturient dairy cow. J Dairy Sci. 1988 Sep;71(9):2572–2583. doi: 10.3168/jds.S0022-0302(88)79846-X. [DOI] [PubMed] [Google Scholar]
  21. Uchida E., Katoh N., Takahashi K. Induction of fatty liver in cows by ethionine administration and concomitant decreases of serum apolipoproteins B-100 and A-I concentrations. Am J Vet Res. 1992 Nov;53(11):2035–2042. [PubMed] [Google Scholar]
  22. Wetherill G. D. Retained placenta in the bovine. A brief review. Can Vet J. 1965 Nov;6(11):290–294. [PMC free article] [PubMed] [Google Scholar]
  23. Yamamoto O., Oikawa S., Katoh N. Enzyme-linked immunosorbent assay for serum apolipoprotein B-100, a major triglyceride-transport protein in dairy cows. Am J Vet Res. 1995 Nov;56(11):1413–1417. [PubMed] [Google Scholar]

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