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Annals of Surgery logoLink to Annals of Surgery
. 1998 Apr;227(4):496–501. doi: 10.1097/00000658-199804000-00008

Use of paravertebral block anesthesia in the surgical management of breast cancer: experience in 156 cases.

E Coveney 1, C R Weltz 1, R Greengrass 1, J D Iglehart 1, G S Leight 1, S M Steele 1, H K Lyerly 1
PMCID: PMC1191303  PMID: 9563536

Abstract

OBJECTIVE: To assess safety and efficacy of the regional anesthetic technique paravertebral block for operative treatment of breast cancer, and to compare postoperative pain, nausea, vomiting, and length of hospital stay in patients undergoing breast surgery using paravertebral block and general anesthesia. BACKGROUND: General anesthesia is currently the standard technique used for surgical treatment of breast cancer. Increasing hospital costs have focused attention on reducing the length of hospital stay for these patients. However, the side effects and complications of general anesthesia preclude ambulatory surgery for most patients undergoing breast surgery. In April 1994, the authors initiated the use of paravertebral block anesthesia for patients undergoing primary breast cancer surgery. A review of our early experience revealed that this regional anesthetic technique enables effective anesthesia for operative procedures of the breast and axilla, reduces postoperative nausea and vomiting, and provides prolonged postoperative sensory block that minimizes narcotic requirements. METHODS: A retrospective analysis of 145 consecutive patients undergoing 156 breast cancer operations using paravertebral block and 100 patients undergoing general anesthesia during a 2-year period was performed. Anesthetic effectiveness and complications, inpatient experience with postoperative pain, nausea, vomiting, and length of stay were measured. RESULTS: Surgery was successfully completed in 85% of the cases attempted by using paravertebral block alone, and in 91% of the cases, surgery was completed by using paravertebral block supplemented with local anesthetic. There was a 2.6% incidence of complications associated with block placement. Twenty percent of patients in the paravertebral group required medication for nausea and vomiting during their hospital stay compared with 39% in the general anesthesia group. Narcotic analgesia was required in 98% of general anesthesia patients, as opposed to 25% of patients undergoing paravertebral block. Ninety-six percent of patients having paravertebral block anesthesia were discharged within the day of surgery, compared with 76% of patients who had a general anesthetic. CONCLUSIONS: Paravertebral block can be used to perform major operations for breast cancer with minimal complications and a low rate of conversion to general anesthesia. Paravertebral block markedly improves the quality of recovery after breast cancer surgery and provides the patient with the option of ambulatory discharge.

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Selected References

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  1. Abramson D. J. 857 breast biopsies as an outpatient procedure: delayed mastectomy in 41 malignant cases. Ann Surg. 1966 Mar;163(3):478–483. doi: 10.1097/00000658-196603000-00021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Atanassoff P. G., Alon E., Weiss B. M. Intercostal nerve block for lumpectomy: superior postoperative pain relief with bupivacaine. J Clin Anesth. 1994 Jan-Feb;6(1):47–51. doi: 10.1016/0952-8180(94)90118-x. [DOI] [PubMed] [Google Scholar]
  3. Bigler D., Dirkes W., Hansen R., Rosenberg J., Kehlet H. Effects of thoracic paravertebral block with bupivacaine versus combined thoracic epidural block with bupivacaine and morphine on pain and pulmonary function after cholecystectomy. Acta Anaesthesiol Scand. 1989 Oct;33(7):561–564. doi: 10.1111/j.1399-6576.1989.tb02966.x. [DOI] [PubMed] [Google Scholar]
  4. Cohen A. M., Schaeffer N., Chen Z. Y., Wood W. C. Early discharge after modified radical mastectomy. Am J Surg. 1986 Apr;151(4):465–466. doi: 10.1016/0002-9610(86)90104-2. [DOI] [PubMed] [Google Scholar]
  5. Devereux D. F. Successful treatment of stages IIIa and IIIb carcinoma of the breast by mastectomy in the elderly high risk patient using local anesthesia. Surg Gynecol Obstet. 1987 Jul;165(1):38–40. [PubMed] [Google Scholar]
  6. Eason M. J., Wyatt R. Paravertebral thoracic block-a reappraisal. Anaesthesia. 1979 Jul-Aug;34(7):638–642. doi: 10.1111/j.1365-2044.1979.tb06363.x. [DOI] [PubMed] [Google Scholar]
  7. Edwards M. J., Broadwater J. R., Bell J. L., Ames F. C., Balch C. M. Economic impact of reducing hospitalization for mastectomy patients. Ann Surg. 1988 Sep;208(3):330–336. doi: 10.1097/00000658-198809000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Fassoulaki A. Brachial plexus block for pain relief after modified radical mastectomy. Anesth Analg. 1982 Dec;61(12):986–987. [PubMed] [Google Scholar]
  9. Greengrass R., O'Brien F., Lyerly K., Hardman D., Gleason D., D'Ercole F., Steele S. Paravertebral block for breast cancer surgery. Can J Anaesth. 1996 Aug;43(8):858–861. doi: 10.1007/BF03013039. [DOI] [PubMed] [Google Scholar]
  10. Hirsch J. Impact of postoperative nausea and vomiting in the surgical setting. Anaesthesia. 1994 Jan;49 (Suppl):30–33. doi: 10.1111/j.1365-2044.1994.tb03580.x. [DOI] [PubMed] [Google Scholar]
  11. Huang T. T., Parks D. H., Lewis S. R. Outpatient breast surgery under intercostal block anesthesia. Plast Reconstr Surg. 1979 Mar;63(3):299–303. doi: 10.1097/00006534-197903000-00001. [DOI] [PubMed] [Google Scholar]
  12. Kirvelä O., Antila H. Thoracic paravertebral block in chronic postoperative pain. Reg Anesth. 1992 Nov-Dec;17(6):348–350. [PubMed] [Google Scholar]
  13. Litvak S., Borrero E., Katz R., Munoz E., Wise L. Early discharge of the postmastectomy patient: unbundling of hospital services to improve profitability under DRGs. Am Surg. 1987 Oct;53(10):577–579. [PubMed] [Google Scholar]
  14. Lynch E. P., Welch K. J., Carabuena J. M., Eberlein T. J. Thoracic epidural anesthesia improves outcome after breast surgery. Ann Surg. 1995 Nov;222(5):663–669. doi: 10.1097/00000658-199511000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Lönnqvist P. A., MacKenzie J., Soni A. K., Conacher I. D. Paravertebral blockade. Failure rate and complications. Anaesthesia. 1995 Sep;50(9):813–815. doi: 10.1111/j.1365-2044.1995.tb06148.x. [DOI] [PubMed] [Google Scholar]
  16. Mackenzie J. Pre-operative paravertebral block for peri-operative analgesia. Anaesthesia. 1992 Apr;47(4):353–354. doi: 10.1111/j.1365-2044.1992.tb02182.x. [DOI] [PubMed] [Google Scholar]
  17. McManus S. A., Topp D. A., Hopkins C. Advantages of outpatient breast surgery. Am Surg. 1994 Dec;60(12):967–970. [PubMed] [Google Scholar]
  18. Nesmith R. L., Herring S. H., Marks M. W., Speight K. L., Efird R. C., Rauck R. L. Early experience with high thoracic epidural anesthesia in outpatient submuscular breast augmentation. Ann Plast Surg. 1990 Apr;24(4):299–303. [PubMed] [Google Scholar]
  19. Oakley N., Dennison A. R., Shorthouse A. J. A prospective audit of simple mastectomy under local anaesthesia. Eur J Surg Oncol. 1996 Apr;22(2):134–136. doi: 10.1016/s0748-7983(96)90541-7. [DOI] [PubMed] [Google Scholar]
  20. Orr R. K., Ketcham A. S., Robinson D. S., Moffat F. L., Tennant N. D. Early discharge after mastectomy. A safe way of diminishing hospital costs. Am Surg. 1987 Mar;53(3):161–163. [PubMed] [Google Scholar]
  21. Parker S. L., Tong T., Bolden S., Wingo P. A. Cancer statistics, 1996. CA Cancer J Clin. 1996 Jan-Feb;46(1):5–27. doi: 10.3322/canjclin.46.1.5. [DOI] [PubMed] [Google Scholar]
  22. Peterson D. O. Shoulder block anesthesia for shoulder reconstruction surgery. Anesth Analg. 1985 Mar;64(3):373–375. [PubMed] [Google Scholar]
  23. Quinn A. C., Brown J. H., Wallace P. G., Asbury A. J. Studies in postoperative sequelae. Nausea and vomiting--still a problem. Anaesthesia. 1994 Jan;49(1):62–65. doi: 10.1111/j.1365-2044.1994.tb03316.x. [DOI] [PubMed] [Google Scholar]
  24. Richardson J., Sabanathan S. Thoracic paravertebral analgesia. Acta Anaesthesiol Scand. 1995 Nov;39(8):1005–1015. doi: 10.1111/j.1399-6576.1995.tb04219.x. [DOI] [PubMed] [Google Scholar]
  25. Romm S., Kennell E., Berggren R. Patient acceptance of intercostal block anesthesia. Plast Reconstr Surg. 1980 Jan;65(1):39–41. doi: 10.1097/00006534-198001000-00008. [DOI] [PubMed] [Google Scholar]
  26. Stein H. D. Ambulatory breast biopsies: the patient's choice. Am Surg. 1982 May;48(5):221–224. [PubMed] [Google Scholar]
  27. Watcha M. F., White P. F. Postoperative nausea and vomiting. Its etiology, treatment, and prevention. Anesthesiology. 1992 Jul;77(1):162–184. doi: 10.1097/00000542-199207000-00023. [DOI] [PubMed] [Google Scholar]
  28. Weltz C. R., Greengrass R. A., Lyerly H. K. Ambulatory surgical management of breast carcinoma using paravertebral block. Ann Surg. 1995 Jul;222(1):19–26. doi: 10.1097/00000658-199507000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]

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