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The Kaohsiung Journal of Medical Sciences logoLink to The Kaohsiung Journal of Medical Sciences
. 2010 Jun 9;26(6):333–336. doi: 10.1016/S1607-551X(10)70048-6

Alexithymia Associated With Bilateral Globus Pallidus Lesions After Carbon Monoxide Poisoning

Mei‐Feng Huang 1, Yi‐Chun Yeh 2, Hin‐Yeung Tsang 1, Cheng‐Sheng Chen 2,3,4,
PMCID: PMC11916439  PMID: 20538239

Abstract

Alexithymia refers to a person's inability to identify and describe feelings. We present a patient who developed alexithymia after carbon monoxide poisoning following a suicide attempt by burning charcoal in an enclosed space. Brain computed tomography revealed bilateral globus pallidus hypoxic lesions. Because of the time frame and the presence of brain structural lesions, the alexithymia in this patient was thought to be caused by bilateral globus pallidus hypoxic lesions resulting from carbon monoxide poisoning. The alexithymia in this patient did not respond to a variety of psychotropic drugs, including sertraline, venalfaxine, bupropion or methylphenidate. We suggest that alexithymia, which was associated with brain hypoxic lesions in this case, is resistant to treatment.

Keywords: alexithymia, carbon monoxide poisoning, globus pallidus

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